Polynucleotides are biostimulating treatments designed to enhance natural radiance, improve complexion, reduce fine lines, and support skin tone and elasticity.
Derived from purified fish sources such as salmon or trout, this injectable gel binds with water to improve tissue firmness and hydration. It can help with wrinkles, scars, brown spots, pores, and stretch marks by neutralising free radicals and supporting collagen, elastin, and hyaluronic acid production. Side effects are usually mild but may include bruising or swelling.
Polynucleotides V Injectable Skin Boosters
Unlike hyaluronic acid skin boosters such as Profhilo, which mainly hydrate, polynucleotides stimulate collagen and elastin production. They can be useful in areas that are harder to treat, including the eyes, lips, and forehead.
By supporting cellular repair, polynucleotides help regenerate existing follicles and encourage the hair growth phase. They also reduce inflammation and improve scalp circulation, helping create a healthier environment for stronger hair.
Suitability & Candidacy
Polynucleotide treatments contain animal-derived ingredients and are unsuitable for vegetarians, vegans, and those with fish allergies. They are also not recommended during pregnancy or breastfeeding. Most other patients may be suitable, but a full medical history is required before treatment.
Treatment Procedure
Typically, polynucleotide treatment involves two to three sessions, spaced about two weeks apart, depending on individual patient needs. Prior to injection, a local anaesthetic cream is applied to numb the target area. The product is then injected into the chosen region of the face or neck. The procedure is relatively brief, and while some discomfort may occur, most patients tolerate it well.
Treatment Areas
Polynucleotides are versatile and can be used across various regions of the face & body. The advent of polynucleotides has been transformative for under-eye procedures, allowing practitioners to treat patients who may not be suitable candidates for tear-trough fillers due to under-eye bags or issues with tissue elasticity. For individuals already receiving tear-trough fillers for hollowing, the addition of polynucleotides often enables longer intervals between filler sessions.
Common treatment areas include:
Brown Spots: Diminishes hyperpigmentation and dark spots
Under Brow Area: Firms sagging skin below the brow
Under-eye Area: Reduces dark circles and fine lines
Face & Neck Rejuvenation: Enhances skin texture and firmness
Décolletage: Improves skin laxity and texture
Hands: Addresses early signs of ageing
Body Areas: Such as the neck, arms, and abdomen for body contouring
Scarring: Effective for treating acne scars, surgical scars, and hypertrophic scars
Hair Restoration: Stimulates hair follicles to promote hair growth in cases of hair loss or thinning
Treatment Results & Package
These treatments are appropriate for both younger and mature patients seeking to improve skin texture and resilience. The best results are often achieved when polynucleotides are incorporated into a comprehensive skincare routine and used alongside other skin treatments. Patients can expect to see results shortly after their initial treatment.
However, to ensure the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available.
Hair loss affects many people and can be emotionally difficult. Polynucleotide treatment offers a non-surgical option for supporting hair restoration where suitable.
For those who may not be suitable for, or ready to consider, hair transplants, polynucleotides may help support existing follicles and improve hair quality.
Polynucleotides Thinning Hair & Hair Loss Treatment represents a significant advancement in addressing thinning hair and promoting effective hair restoration. This innovative procedure utilises an injectable biostimulator solution, comprising fragments derived from fish, which are engineered to closely mimic human DNA. The biological similarity ensures optimal compatibility and effectiveness when administered.
Key Benefits
Awakens dormant hair follicles
Strengthens existing hair follicles
Fuller, thicker & healthier hair
How Polynucleotide Hair Injections Work
The procedure involves injecting a polynucleotide-rich solution into the scalp. This stimulates fibroblasts, supports tissue repair, and boosts collagen levels important for skin and hair health.
By supporting cellular repair, polynucleotides help regenerate existing follicles and encourage the hair growth phase. They also reduce inflammation and improve scalp circulation, helping create a healthier environment for stronger hair.
Limitations of Polynucleotide Hair Loss Treatment
Polynucleotide hair-loss treatments are not suitable for total baldness or fully bald patches. Some existing hair must be present, as the treatment works by stimulating and supporting remaining follicles.
See also ‘Aesthetics – Dermapen – Dermapen Hair Loss Treatment.
How the Treatment Works
Upon injection into the scalp, the solution reactivates dormant hair follicles, stimulating them to generate the essential elements required for stronger hair growth. This process not only strengthens existing follicles but also contributes to the overall revitalisation of the scalp. By encouraging natural hair regeneration, individuals experiencing hair loss can achieve a fuller, thicker, and healthier head of hair.
Results & Treatment Schedule
Patients can expect to see results shortly after their initial treatment. However, to maintain the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results.
The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available.
Pricing Options
The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available.
Patients generally begin to see improvements soon after the initial session, with the second session accelerating the remodelling process. Polynucleotides continue to work for the first 12 weeks, providing progressive enhancements over time. Notably, patients often experience early improvement and lifting effects following the first session. Results typically last about six months before a maintenance session is required.
Patients can expect to see results shortly after their initial treatment. However, to maintain the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results.
The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available.
Polynucleotides are highly versatile and compatible with various energy-based treatments. They can target concerns such as dark circles, under-eye hollowing, and crepey skin around the eyes. These treatments may be combined with radio frequency skin-tightening or skin needling procedures. Polynucleotides can also be used alongside dermal fillers, such as incorporating them into a tear-trough treatment plan to enhance skin quality. It is essential to evaluate each patient’s needs during consultation to create tailored treatment plans that ensure realistic goals and safe, effective outcomes
| Pre-Treatment Aesthetic Consultation | Polynecleotides | 30 min | £50 | A pre-treatment consultation holds equal significance to the actual aesthetic procedure. Clients are strongly encouraged to participate in an informal discussion, which provides an opportunity to gain a deeper understanding of the process ahead. This session is designed to foster a professional relationship between Dr Teresa Day and her clients, ensuring that all concerns are addressed and expectations are clearly established. Drawing upon her extensive experience, Dr Teresa Day carefully listens to each client’s individual needs and objectives. She discusses any specific concerns, explores desired outcomes, and then recommends a personalised treatment plan tailored to each person’s requirements. Importantly, the consultation fee is entirely redeemable against the cost of any aesthetic treatment, provided the treatment is completed within 6 weeks of the initial consultation. |
| Polynucleotides - Face Rejuvenation | 45 min | £300 | An inevitable aspect of ageing for all of us is skin that is looser, thinner and therefore more lined. For many people, this can result in areas of skin that appear thinner and finely wrinkled, like crepe paper. Patients can expect to see results shortly after their initial treatment. However, to ensure the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available. |
| Polynucleotides - Neck Rejuvenation | 45 min | £300 | An inevitable aspect of ageing for all of us is skin that is looser, thinner and therefore more lined. For many people, this can result in areas of skin that appear thinner and finely wrinkled, like crepe paper. Patients can expect to see results shortly after their initial treatment. However, to ensure the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available. |
| Polynucleotides – Decolletage Rejuvenation | 45 min | £300 | An inevitable aspect of ageing for all of us is skin that is looser, thinner and therefore more lined. For many people, this can result in areas of skin that appear thinner and finely wrinkled, like crepe paper. Patients can expect to see results shortly after their initial treatment. However, to ensure the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available. |
| Polynucleotides – Under Eye Area | 45 min | £300 | As we age, the skin here loses volume and can become thinner and more vulnerable to sagging. The tear trough can become deeper and darker, and eye bags can start to form. This can lead to an appearance of tiredness and make us look older Patients can expect to see results shortly after their initial treatment. However, to ensure the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available. |
| Polynucleotides – Under Brow Area | 45 min | £300 | Polynucleotides are particularly effective in the under-eye area, where they improve skin quality, reduce dark circles, and target fine lines without the risk of puffiness. This makes them a popular alternative to traditional under-eye fillers. Patients can expect to see results shortly after their initial treatment. However, to ensure the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available. |
| Polynucleotides – Scarring | 45 min | £300 | Polynucleotides have shown promise in supporting the treatment of certain types of scarring, particularly acne scarring. Patients can expect to see results shortly after their initial treatment. However, to ensure the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available. |
| Polynucleotides – Brown Spots | 45 min | £300 | Patients can expect to see results shortly after their initial treatment. However, to ensure the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available. |
| Polynucleotides – Thinning Hair & Hair Loss Treatment | 45 min | £300 |
Polynucleotides Hair Loss Treatment represents a significant advancement in addressing thinning hair and promoting effective hair restoration. This innovative procedure utilises an injectable biostimulator solution, comprising fragments derived from fish, which are engineered to closely mimic human DNA. The biological similarity ensures optimal compatibility and effectiveness when administered. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available. |
| Polynucleotides – Body Rejuvenation | 45 min | £300 | Price is per area. Please select you area of treatment: Hands Upper Arms Abdomen Body Contouring Patients can expect to see results shortly after their initial treatment. However, to ensure the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, a Package of 3 treatments is also available. |
| Polynucleotides - Package of 3 Treatments | - | £800 | Patients can expect to see results shortly after their initial treatment. However, to maintain the modelling process continues effectively, a total of 3 sessions is recommended. The beneficial effects of polynucleotides last for up to 6 months, after which it is advised to book a maintenance treatment to preserve results. The price listed applies to a single treatment session. For those seeking comprehensive care, this Package of 3 treatments is also available. |